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agarose bound pna  (Vector Laboratories)


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    Vector Laboratories agarose bound pna
    Agarose Bound Pna, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 92/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/AL-1073/pm40024474-177-17-19?v=Vector+Laboratories
    Average 92 stars, based on 31 article reviews
    agarose bound pna - by Bioz Stars, 2026-07
    92/100 stars

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    LC‒MS/MS analysis of PNA-purified proteins derived from the pancreas of WT and GalNT2-TG mice. (A) Comparative staining of Tn antigen (VVA) and core-1 (PNA) in tissue sections of adult WT and Cosmc-KO murine pancreata. The magnification is 200x. (B) Biosynthesis pathway of O-glycans. Starting from a polypeptide, selected serines and tyrosines are modified by GalNT2 (and other ppGalNAcTs) with O-GalNAc (Tn antigen). This glycan is elongated by T-synthase to core-1, which is bound by PNA. (C) Venn diagram of identified PNA-purified proteins from WT and GalNT2-TG pancreata ( n = 2 each) and pathway analysis of WT proteins, including common and exclusively TG-derived proteins.

    Journal: Scientific Reports

    Article Title: GalNT2-mediated O-glycosylation affects pancreas development and function in mice

    doi: 10.1038/s41598-024-80276-7

    Figure Lengend Snippet: LC‒MS/MS analysis of PNA-purified proteins derived from the pancreas of WT and GalNT2-TG mice. (A) Comparative staining of Tn antigen (VVA) and core-1 (PNA) in tissue sections of adult WT and Cosmc-KO murine pancreata. The magnification is 200x. (B) Biosynthesis pathway of O-glycans. Starting from a polypeptide, selected serines and tyrosines are modified by GalNT2 (and other ppGalNAcTs) with O-GalNAc (Tn antigen). This glycan is elongated by T-synthase to core-1, which is bound by PNA. (C) Venn diagram of identified PNA-purified proteins from WT and GalNT2-TG pancreata ( n = 2 each) and pathway analysis of WT proteins, including common and exclusively TG-derived proteins.

    Article Snippet: In brief, agarose-bound PNA (AL-1073, Vector Laboratories) was used to enrich nonsialylated core 1-modified proteins, along with their potential interactors, from pancreatic lysates of WT and GalNT2-TG het mice at 7 weeks of age (2 biological replicates per group).

    Techniques: Purification, Derivative Assay, Staining, Modification

    Journal: iScience

    Article Title: Stenotrophomonas maltophilia provokes NEU1-mediated release of a flagellin-binding decoy receptor that protects against lethal infection

    doi: 10.1016/j.isci.2024.110866

    Figure Lengend Snippet:

    Article Snippet: PNA-agarose , Vector Laboratories , Cat# AL-1073.

    Techniques: Virus, Recombinant, Control, Software, Plasmid Preparation, Enzyme-linked Immunosorbent Assay